Wayne J. Fairbrother : rechercher sur Z-Library

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1

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

Souers, Andrew J, Leverson, Joel D, Boghaert, Erwin R, Ackler, Scott L, Catron, Nathaniel D, Chen, Jun, Dayton, Brian D, Ding, Hong, Enschede, Sari H, Fairbrother, Wayne J, Huang, David C S, Hymowitz,

Journal:

Nature Medicine

Année:

2013

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2013

2

Novel Peptides Selected to Bind Vascular Endothelial Growth Factor Target the Receptor-Binding Site

Fairbrother, Wayne J., Christinger, Hans W., Cochran, Andrea G., Fuh, Germaine, Keenan, Christopher J., Quan, Clifford, Shriver, Stephanie K., Tom, Jeffrey Y. K., Wells, James A., Cunningham, Brian C.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 459 KB

english, 1998

3

Designer Proteins to Trigger Cell Death

Fairbrother, Wayne J., Ashkenazi, Avi

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 320 KB

english, 2014

4

From basic apoptosis discoveries to advanced selective BCL-2 family inhibitors

Ashkenazi, Avi, Fairbrother, Wayne J., Leverson, Joel D., Souers, Andrew J.

Journal:

Nature Reviews Drug Discovery

Année:

2017

Langue:

english

Fichier:

PDF, 752 KB

english, 2017

5

Cover Picture: ChemBioChem 1/2003

Sachdev S. Sidhu, Wayne J. Fairbrother, Kurt Deshayes

Journal:

Année:

2003

Fichier:

PDF, 19 KB

2003

6

Exploring Protein–Protein Interactions with Phage Display

Sachdev S. Sidhu, Wayne J. Fairbrother, Kurt Deshayes

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 486 KB

english, 2003

7

Exploring Protein—Protein Interactions with Phage Display

Sachdev S. Sidhu, Wayne J. Fairbrother, Kurt Deshayes

Journal:

Année:

2003

Fichier:

PDF, 51 KB

2003

8

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1H and natural abundance 13C NMR spectroscopy

Neil E. Jacobsen, Wayne J. Fairbrother, Charlotte R. Kensil, Amy Lim, Deborah A. Wheeler, Michael F. Powell

Journal:

Carbohydrate Research

Année:

1996

Langue:

english

Fichier:

PDF, 670 KB

english, 1996

9

Characterization of the structure and properties of the His 62 → Ala and Arg 38 → Ala mutants of yeast phosphoglycerate kinase: An investigation of the catalytic and activatory sites by site-directed mutagenesis and NMR

Mark A. Sherman, Maria T. Mas, Wayne J. Fairbrother

Journal:

Protein Science

Année:

1992

Langue:

english

Fichier:

PDF, 2.59 MB

english, 1992

10

Monomeric variants of IL-8: Effects of side chain substitutions and solution conditions upon dimer formation

Henry B. Lowman, Wayne J. Fairbrother, Paul H. Slagle, Rhona Kabakoff, Caroline A. Hebert, Jun Liu, Steven Shire

Journal:

Protein Science

Année:

1997

Langue:

english

Fichier:

PDF, 3.05 MB

english, 1997

11

1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor

Wayne J. Fairbrother, Mark A. Champe, Hans W. Christinger, Bruce A. Keyt, Melissa A. Starovasnik

Journal:

Protein Science

Année:

1997

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1997

12

A novel isotope labeling protocol for bacterially expressed proteins

Dorothea Reilly, Wayne J. Fairbrother

Journal:

Journal of Biomolecular NMR

Année:

1994

Langue:

english

Fichier:

PDF, 374 KB

english, 1994

13

Improved resolution in three-dimensional constant-time triple resonance NMR spectroscopy of proteins

Arthur G. Palmer, Wayne J. Fairbrother, John Cavanagh, Peter E. Wright, Mark Rance

Journal:

Journal of Biomolecular NMR

Année:

1992

Langue:

english

Fichier:

PDF, 337 KB

english, 1992

14

Letters to the Editor1H,13C, and15N resonance assignments of SAP18

Scott A. McCallum, JianPing Yin, Wayne J. Fairbrother

Journal:

Journal of Biomolecular NMR

Année:

2005

Langue:

english

Fichier:

PDF, 177 KB

english, 2005

15

NMR assignments of the human cytokine interleukin-33

Andreas Lingel, Wayne J. Fairbrother

Journal:

Biomolecular NMR Assignments

Année:

2009

Langue:

english

Fichier:

PDF, 832 KB

english, 2009

16

Compounds in the droplets of the orb spider's viscid spiral

Vollrath, Fritz, Fairbrother, Wayne J., Williams, Robert J. P., Tillinghast, Edward K., Bernstein, David T., Gallagher, Kathleen S., Townley, Mark A.

Journal:

Année:

1990

Fichier:

PDF, 621 KB

1990

17

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

Dynek, Jasmin N, Goncharov, Tatiana, Dueber, Erin C, Fedorova, Anna V, Izrael-Tomasevic, Anita, Phu, Lilian, Helgason, Elizabeth, Fairbrother, Wayne J, Deshayes, Kurt, Kirkpatrick, Donald S

Journal:

The EMBO Journal

Année:

2010

Langue:

english

Fichier:

PDF, 872 KB

english, 2010

18

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

Wiesmann, Christian, Katschke, Kenneth J., Yin, JianPing, Helmy, Karim Y., Steffek, Micah, Fairbrother, Wayne J., McCallum, Scott A., Embuscado, Lizette, DeForge, Laura, Hass, Philip E.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 926 KB

english, 2006

19

Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

Gitschier, Jane, Moffat, Barbara, Reilly, Dorothea, Wood, William I., Fairbrother, Wayne J.

Journal:

Natural Structural Biology

Année:

1998

Fichier:

PDF, 1.57 MB

1998

20

Letter to the Editor:1H,13C, and15N resonance assignment of the vascular endothelial growth factor receptor-binding domain in complex with a receptor-blocking peptide

Borlan Pan, Wayne J. Fairbrother

Journal:

Journal of Biomolecular NMR

Année:

2002

Langue:

english

Fichier:

PDF, 74 KB

english, 2002

21

Refinement of the solution structure of the heparin-binding domain of vascular endothelial growth factor using residual dipolar couplings

Melissa E. Stauffer, Nicholas J. Skelton, Wayne J. Fairbrother

Journal:

Journal of Biomolecular NMR

Année:

2002

Langue:

english

Fichier:

PDF, 110 KB

english, 2002

22

The PYRIN domain: A member of the death domain-fold superfamily

Wayne J. Fairbrother, Nathaniel C. Gordon, Eric W. Humke, Karen M. O'Rourke, Melissa A. Starovasnik, Jian-Ping Yin, Vishva M. Dixit

Journal:

Protein Science

Année:

2001

Langue:

english

Fichier:

PDF, 293 KB

english, 2001

23

Antibody variable region binding by Staphylococcal protein A: Thermodynamic analysis and location of the Fv binding site on E-domain

Melissa A. Starovasnik, Mark P. O'Connell, Wayne J. Fairbrother, Robert F. Kelley

Journal:

Protein Science

Année:

1999

Langue:

english

Fichier:

PDF, 1.70 MB

english, 1999

24

Convergent Recognition of the IgE Binding Site on the High-Affinity IgE Receptor

Jennifer Stamos, Charles Eigenbrot, Gerald R Nakamura, Mark E Reynolds, JianPing Yin, Henry B Lowman, Wayne J Fairbrother, Melissa A Starovasnik

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 623 KB

english, 2004

25

Structure of IL-33 and Its Interaction with the ST2 and IL-1RAcP Receptors—Insight into Heterotrimeric IL-1 Signaling Complexes

Andreas Lingel, Thomas M. Weiss, Marc Niebuhr, Borlan Pan, Brent A. Appleton, Christian Wiesmann, J. Fernando Bazan, Wayne J. Fairbrother

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2009

26

Identification of a Novel Death Domain-Containing Adaptor Molecule for Ectodysplasin-A Receptor that Is Mutated in crinkled Mice

Minhong Yan, Zemin Zhang, John Ridgway Brady, Sarah Schilbach, Wayne J. Fairbrother, Vishva M. Dixit

Journal:

Current Biology

Année:

2002

Langue:

english

Fichier:

PDF, 281 KB

english, 2002

27

Solution structure of the heparin-binding domain of vascular endothelial growth factor

Wayne J Fairbrother, Mark A Champe, Hans W Christinger, Bruce A Keyt, Melissa A Starovasnik

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 273 KB

english, 1998

28

NMR analysis of site-specific mutants of yeast phosphoglycerate kinase : An investigation of the triose-binding site

Wayne J. FAIRBROTHER, Philip A. WALKER, Philippe MINARD, Jennifer A. LITTLECHILD, Herman C. WATSON, Robert J. P. WILLIAMS

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1989

29

One- and two-dimensional NMR studies of yeast phosphoglycerate kinase

Wayne J. FAIRBROTHER, Derrick BOWEN, Len HALL, Robert J. P. WILLIAMS

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 948 KB

english, 1989

30

An NMR study of anion binding to yeast phosphoglycerate kinase

Wayne J. FAIRBROTHER, Heidi C. GRAHAM, Robert J. P. WILLIAMS

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 874 KB

english, 1990

31

The roles of ATP4− and Mg2+ in control steps of phosphoglycerate kinase

Wayne J. FAIRBROTHER, Heidi C. GRAHAM, Robert J. P. WILLIAMS

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 759 KB

english, 1990

32

The Solution Structure of Melanoma Growth Stimulating Activity

Wayne J. Fairbrother, Dorothea Reilly, Timothy J. Colby, Joseph Hesselgesser, Richard Horuk

Journal:

Journal of Molecular Biology

Année:

1994

Fichier:

PDF, 1.42 MB

1994

33

Backbone dynamics of the EGF-like domain of heregulin-α

Wayne J. Fairbrother, Jun Liu, Paul I. Pisacane, Mark X. Sliwkowski, Arthur G. Palmer III

Journal:

Journal of Molecular Biology

Année:

1998

Langue:

english

Fichier:

PDF, 707 KB

english, 1998

34

Solution structure of a phage-derived peptide antagonist in complex with vascular endothelial growth factor

Borlan Pan, Bing Li, Stephen J Russell, Jeffrey Y.K Tom, Andrea G Cochran, Wayne J Fairbrother

Journal:

Journal of Molecular Biology

Année:

2002

Langue:

english

Fichier:

PDF, 905 KB

english, 2002

35

Site-directed mutagenesis of histidine 62 in the ‘basic patch’ region of yeast phosphoglycerate kinase

Wayne J. Fairbrother, Len Hall, Jennifer A. Littlechild, Philip A. Walker, Herman C. Watson, Robert J.P. Williams

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 490 KB

english, 1989

36

Low resolution solution structure of the Bacillus subtilis glucose permease IIA domain derived from heteronuclear three-dimensional NMR spectroscopy

Wayne J. Fairbrother, Garry P. Gippert, Jonathan Reizer, Milton H. Saier Jr., Peter E. Wright

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 530 KB

english, 1992

37

1H assignment and secondary structure determination of human melanoma growth stimulating activity (MGSA) by NMR spectroscopy

Wayne J. Fairbrother, Dorothea Reilly, Timothy Colby, Richard Horuk

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 491 KB

english, 1993

38

Peptide substrate profiling defines fibroblast activation protein as an endopeptidase of strict Gly2-Pro1-cleaving specificity

Conrad Yap Edosada, Clifford Quan, Thuy Tran, Victoria Pham, Christian Wiesmann, Wayne Fairbrother, Beni B. Wolf

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 223 KB

english, 2006

39

The Structure of the Extracellular Domain of the Jumping Translocation Breakpoint Protein Reveals a Variation of the Midkine Fold

Francois Rousseau, Borlan Pan, Wayne J. Fairbrother, J. Fernando Bazan, Andreas Lingel

Journal:

Journal of Molecular Biology

Année:

2012

Langue:

english

Fichier:

PDF, 494 KB

english, 2012

40

ICEBERG: A Novel Inhibitor of Interleukin-1β Generation

Eric W Humke, Stephanie K Shriver, Melissa A Starovasnik, Wayne J Fairbrother, Vishva M Dixit

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 642 KB

english, 2000

41

Structure of SAP18: A Ubiquitin Fold in Histone Deacetylase Complex Assembly ‡

McCallum, Scott A., Bazan, J. Fernando, Merchant, Mark, Yin, JianPing, Pan, Borlan, de Sauvage, Frederic J., Fairbrother, Wayne J.

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 479 KB

english, 2006

42

An NMR analysis of the binding of inhibitors to yeast phosphoglycerate kinase

Helena A. BOYLE, Wayne J. FAIRBROTHER, Robert J. P. WILLIAMS

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 844 KB

english, 1989

43

Solution Structure of the E-Domain of Staphylococcal Protein A ‡

Starovasnik, Melissa A., Skelton, Nicholas J., O'Connell, Mark P., Kelley, Robert F., Reilly, Dorothea, Fairbrother, Wayne J.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 758 KB

english, 1996

44

Structure-guided design of a selective BCL-XL inhibitor

Lessene, Guillaume, Czabotar, Peter E, Sleebs, Brad E, Zobel, Kerry, Lowes, Kym N, Adams, Jerry M, Baell, Jonathan B, Colman, Peter M, Deshayes, Kurt, Fairbrother, Wayne J, Flygare, John A, Gibbons, P

Journal:

Nature Chemical Biology

Année:

2013

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2013

45

Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity

Sleebs, Brad E., Czabotar, Peter E., Fairbrother, Wayne J., Fairlie, W. Douglas, Flygare, John A., Huang, David C. S., Kersten, Wilhelmus J. A., Koehler, Michael F. T., Lessene, Guillaume, Lowes, Kym,

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2011

46

High-Resolution Solution Structure of the EGF-like Domain of Heregulin-α ‡

Jacobsen, Neil E., Abadi, Nasrin, Sliwkowski, Mark X., Reilly, Dorothea, Skelton, Nicholas J., Fairbrother, Wayne J.

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 805 KB

english, 1996

47

[Methods in Enzymology] Chemokines Volume 287 || Molecular approaches to structure-function analysis of interleukin-8

Fairbrother, Wayne J.

Année:

1997

Langue:

english

Fichier:

PDF, 708 KB

english, 1997

48

Internal Motions Prime cIAP1 for Rapid Activation

Phillips, Aaron H., Schoeffler, Allyn J., Matsui, Tsutomu, Weiss, Thomas, Dueber, Erin C., Fairbrother, Wayne J.

Journal:

Biophysical Journal

Année:

2014

Langue:

english

Fichier:

PDF, 46 KB

english, 2014

49

Protein NMR Techniquesby David G. Reid

Review by: Wayne J. Fairbrother

Journal:

Quarterly Review of Biology

Année:

1999

Langue:

english

Fichier:

PDF, 130 KB

english, 1999

50

Small-molecule pan-IAP antagonists: a patent review

Flygare, John A, Fairbrother, Wayne J

Journal:

Expert Opinion on Therapeutic Patents

Année:

2010

Langue:

english

Fichier:

PDF, 474 KB

english, 2010